Process Modeling and Automated Execution for Bio-Manufacturing

نویسندگان

  • Zhiqi Shen
  • Robert Gay
  • Chunyan Miao
  • Tin Wee Tan
  • Chong Sean Kuay
  • Hui Mien Lee
چکیده

Recently there is a great demand for extending high throughput life science research to biomanufacturing. However, there is a gap from life science research to bio-manufacturing. Most of existing Bio-workflow tools/systems only provide an isolated solution to help bioscientist to orchestrate bio-R&D operations such as bio-database query, bio-computation and analysis etc for specific small bio-problems. They are static and lack of ability to adapt themselves in a dynamic changing environment. Bio-manufacturing involves many bioprocesses, each of which needs to choreographs a set of bio-workflows. Currently, none of the existing workflow systems support integrations of workflows from different workflow tools. Bio-scientists have to manually define and manage the workflows for bioprocesses through different workflow tools. This paper proposes a novel goal-oriented approach to modeling bioprocesses, to choreographing bio-workflows from different workflow tools, and to integrating agents, web services and workflows for automated execution. It also demonstrates how a multi-agent system can be further derived to adapt and automate complex bio-manufacturing workflow/processes in a dynamic changing environment.

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تاریخ انتشار 1997